BDBM30853 2-(5-fluoranyl-1H-indol-3-yl)ethanamine;hydrochloride::2-(5-fluoro-1H-indol-3-yl)ethanamine;hydrochloride::2-(5-fluoro-1H-indol-3-yl)ethylamine;hydrochloride::5-F-T::CHEMBL275628::MLS000047815::SMR000033820::cid_197774

SMILES NCCc1c[nH]c2ccc(F)cc12

InChI Key InChIKey=ZKIORVIXEWIOGB-UHFFFAOYSA-N

Data  2 KI  5 IC50  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 30853   

Target5-hydroxytryptamine receptor 1A(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataEC50:  2.22E+3nMpH: 7.4 T: 2°CAssay Description:A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
Target5-hydroxytryptamine receptor 1E(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataEC50:  484nMpH: 7.4 T: 2°CAssay Description:The CHO cell line was cultured in T-175 sq cm Corning flasks (part 431080) at 37 deg C and 95% RH. The HTS assay began by dispensing 10 microliters o...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
Target5-hydroxytryptamine receptor 1A(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataEC50:  1.86E+4nMpH: 7.4 T: 2°CAssay Description:A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetSphingosine 1-phosphate receptor 3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataEC50: >4.00E+4nMAssay Description:External Assay ID: S1P3_EC50_CS_5HT1e_Agonist Name: S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataEC50:  10nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataEC50:  464nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataEC50:  82nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at 5HT2A receptor (unknown origin) by cell based calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMyeloperoxidase(Human)
Universite£? Libre De Bruxelles

Curated by ChEMBL
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant MPO mediated taurine chlorination by microplate reader methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMyeloperoxidase(Human)
Universite£? Libre De Bruxelles

Curated by ChEMBL
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataIC50: 940nMAssay Description:Inhibition of recombinant MPO mediated LDL oxidation using MPO/Cl-/H2O2 systemMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataIC50: 1.23E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataIC50: 1.31E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMyeloperoxidase(Human)
Universite£? Libre De Bruxelles

Curated by ChEMBL
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataIC50: 790nMAssay Description:Inhibition of recombinant human myeloperoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataKi:  5.65nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataKi:  11nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed