BDBM50010618 (+)-3-(1-Propyl-piperidin-3-yl)-phenol::3-((R)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(-)::CHEMBL7393::cid_202478

SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1

InChI Key InChIKey=HTSNFXAICLXZMA-UHFFFAOYSA-N

Data  8 KI  9 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50010618   

TargetSigma non-opioid intracellular receptor 1(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataIC50: 32nMAssay Description:In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataIC50: 930nMAssay Description:In vitro inhibition of [3H]haloperidol (HPD) binding to dopamine (DA) receptor of rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2019
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataIC50: 98nMAssay Description:In vitro inhibition of [3H]N-0437 binding to Dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataIC50: 1.71E+3nMAssay Description:Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataIC50: 230nMAssay Description:Displacement of spiperone from dopamine receptor D2 of rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2014
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataIC50: 1.52E+3nMAssay Description:Displacement of (+)-3PPP from sigma receptor of rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataIC50: 2.30E+4nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Mouse)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataEC50:  7.61E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetMu-type opioid receptor(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataEC50:  9.25E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Assay Provider: Laura Bohn External Assay ID: OPRM1_AC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetSigma non-opioid intracellular receptor 1(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataKi:  6nMAssay Description:Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataKi:  155nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataKi:  162nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataKi:  189nMAssay Description:In vitro affinity against Dopamine receptor D2 using [3H]DP-5,6-ADTN radioligand in rat striatal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataKi:  235nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataKi:  280nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
TargetC-8 sterol isomerase ERG2(Baker's yeast)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataKi:  1.20E+3nMAssay Description:Affinity for ERG2 of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataKi:  2.20E+3nMAssay Description:Affinity for human EMP expressed in ERG2 deficient strain of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed