BDBM91621 21q::alpha7 agonists 21q

SMILES Cc1cc(C)nc(SCCCc2cn(nn2)[C@H]2C[C@@H]3CC[C@H](C2)[N+]3(C)C)n1

InChI Key InChIKey=VZADPKKBVQKZLB-UHFFFAOYSA-N

Data  6 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 91621   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of California San Diego

LigandPNGBDBM91621(21q | alpha7 agonists 21q)
Affinity DataEC50:  3.00E+3nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSoluble acetylcholine receptor(California sea hare)
University of California San Diego

LigandPNGBDBM91621(21q | alpha7 agonists 21q)
Affinity DataKi:  18nM ΔG°:  -10.4kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSoluble acetylcholine receptor(California sea hare)
University of California San Diego

LigandPNGBDBM91621(21q | alpha7 agonists 21q)
Affinity DataKi:  30nM ΔG°:  -10.1kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of California San Diego

LigandPNGBDBM91621(21q | alpha7 agonists 21q)
Affinity DataKi:  40nM ΔG°:  -9.92kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSoluble acetylcholine receptor(California sea hare)
University of California San Diego

LigandPNGBDBM91621(21q | alpha7 agonists 21q)
Affinity DataKi:  400nM ΔG°:  -8.58kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of California San Diego

LigandPNGBDBM91621(21q | alpha7 agonists 21q)
Affinity DataKi:  2.71E+4nM ΔG°:  -6.48kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A(Mouse)
University of California San Diego

LigandPNGBDBM91621(21q | alpha7 agonists 21q)
Affinity DataKi: >3.00E+4nM ΔG°: >-6.41kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed