BDBM50346865 2-PFPA::CHEMBL1797642

SMILES NC1CC1c1c(F)c(F)c(F)c(F)c1F

InChI Key InChIKey=NZZZWLLBMMVQQY-UHFFFAOYSA-N

Data  7 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50346865   

TargetLysine-specific histone demethylase 1A(Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM50346865(CHEMBL1797642 | 2-PFPA)
Affinity DataIC50: 8.90E+3nMAssay Description:The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM50346865(CHEMBL1797642 | 2-PFPA)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM50346865(CHEMBL1797642 | 2-PFPA)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of hexahistidine-tagged LSD1 (unknown origin) (172 to 833 residues) expressed in Escherichia coli Rosetta (DE3) cells using H3K4me2 peptid...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50346865(CHEMBL1797642 | 2-PFPA)
Affinity DataKi:  8.30E+3nMAssay Description:Inhibition of human MAO-B expressed in expressed in baculovirus infected BTI insect cells using tyramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50346865(CHEMBL1797642 | 2-PFPA)
Affinity DataKi:  8.30E+3nMAssay Description:Inhibition of human recombinant MAO-B using tyramine as substrate assessed as inhibition constant by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM50346865(CHEMBL1797642 | 2-PFPA)
Affinity DataKi:  8.90E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM50346865(CHEMBL1797642 | 2-PFPA)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of hexahistidine-tagged human LSD1 (172 to 833 residues) expressed in Escherichia coli Rosetta (DE3) cells using H3K4me2 peptide as substr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM50346865(CHEMBL1797642 | 2-PFPA)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of hexahistidine-tagged LSD1 (unknown origin) (172 to 833 residues) expressed in Escherichia coli Rosetta (DE3) cells using H3K4me2 peptid...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50346865(CHEMBL1797642 | 2-PFPA)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of human recombinant MAO-A using tyramine as substrate assessed as inhibition constant by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50346865(CHEMBL1797642 | 2-PFPA)
Affinity DataKi:  2.70E+5nMAssay Description:Inhibition of human MAO-A expressed in expressed in baculovirus infected BTI insect cells using tyramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed