BDBM50017041 (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline::1,2,3,4-Tetrahydro-1-(phenylmethyl)isoquinoline::1BnTIQ::CHEMBL21640::rac-(1R)-1-benzyl-1,2,3,4-tetrahydroisoquinoline

SMILES C(C1NCCc2ccccc12)c1ccccc1

InChI Key InChIKey=YRYCIFUZSUMAAY-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50017041   

TargetSigma non-opioid intracellular receptor 1(Rat)
G. D. Searle

Curated by ChEMBL
LigandPNGBDBM50017041(1,2,3,4-Tetrahydro-1-(phenylmethyl)isoquinoline | ...)
Affinity DataIC50: 430nMAssay Description:Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
G. D. Searle

Curated by ChEMBL
LigandPNGBDBM50017041(1,2,3,4-Tetrahydro-1-(phenylmethyl)isoquinoline | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50017041(1,2,3,4-Tetrahydro-1-(phenylmethyl)isoquinoline | ...)
Affinity DataIC50: 8.21E+4nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of MPP+ after 1 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50017041(1,2,3,4-Tetrahydro-1-(phenylmethyl)isoquinoline | ...)
Affinity DataKi:  3.57E+3nMAssay Description:The compound has been evaluated for its binding affinity towards Dopamine receptor D2 by displacing the radioligand [3H]YM-09151-2 (0.5 nM) in rat st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50017041(1,2,3,4-Tetrahydro-1-(phenylmethyl)isoquinoline | ...)
Affinity DataKi:  3.66E+4nMAssay Description:The compound has been evaluated for its binding affinity towards Dopamine transporter by displacing the radioligand [3H]GBR-12935 (1.0 nM) in rat str...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50017041(1,2,3,4-Tetrahydro-1-(phenylmethyl)isoquinoline | ...)
Affinity DataKi:  2.49E+5nMAssay Description:The compound has been evaluated for its binding affinity towards Dopamine receptor D1 by displacing the radioligand [3H]SCH-23390 (1.5 nM) in rat str...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed