BDBM50240485 18:0::C18:0::CH3-[CH2]16-COOH::CHEMBL46403::Octadecanoic acid::Octadecansaeure::Oktadekansaeure::Stearinsaeure::acide octadecanoique::acide stearique::n-octadecanoic acid::octadecoic acid::stearic acid

SMILES CCCCCCCCCCCCCCCCCC(=O)O

InChI Key InChIKey=QIQXTHQIDYTFRH-UHFFFAOYSA-N

Data  2 KI  7 IC50  1 Kd  1 EC50

PDB links: 84 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50240485   

TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50240485(stearic acid | 18:0 | C18:0 | CH3-[CH2]16-COOH | O...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50240485(stearic acid | 18:0 | C18:0 | CH3-[CH2]16-COOH | O...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50240485(stearic acid | 18:0 | C18:0 | CH3-[CH2]16-COOH | O...)
Affinity DataKd:  8.00E+4nMAssay Description:Binding affinity against Adipocyte lipid binding proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Electric eel)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50240485(stearic acid | 18:0 | C18:0 | CH3-[CH2]16-COOH | O...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured at 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50240485(stearic acid | 18:0 | C18:0 | CH3-[CH2]16-COOH | O...)
Affinity DataIC50: 6.00E+3nMAssay Description:Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

LigandPNGBDBM50240485(stearic acid | 18:0 | C18:0 | CH3-[CH2]16-COOH | O...)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

LigandPNGBDBM50240485(stearic acid | 18:0 | C18:0 | CH3-[CH2]16-COOH | O...)
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50240485(stearic acid | 18:0 | C18:0 | CH3-[CH2]16-COOH | O...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 30 mins by photometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM50240485(stearic acid | 18:0 | C18:0 | CH3-[CH2]16-COOH | O...)
Affinity DataEC50:  4.00E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Electric eel)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50240485(stearic acid | 18:0 | C18:0 | CH3-[CH2]16-COOH | O...)
Affinity DataKi:  3.62E+3nMAssay Description:Mixed type inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50240485(stearic acid | 18:0 | C18:0 | CH3-[CH2]16-COOH | O...)
Affinity DataKi:  4.40E+3nMAssay Description:Mixed type inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed