BDBM12466 (2S)-1-[2-(adamantan-1-ylamino)acetyl]pyrrolidine-2-carbonitrile::1-[(1-Adamantylamino)acetyl]-2-pyrrolidinecarbonitrile::17b::Amide Analogue 48

SMILES O=C(CNC12CC3CC(CC(C3)C1)C2)N1CCC[C@H]1C#N

InChI Key InChIKey=GFJBFJGNXDVDDX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12466   

TargetDipeptidyl peptidase 4(Human)
University of Antwerp

LigandPNGBDBM12466(1-[(1-Adamantylamino)acetyl]-2-pyrrolidinecarbonit...)
Affinity DataIC50: 350nMAssay Description:The DPP inhibition was measured by monitoring the cleavage of chromogenic substrate in the presence of each inhibitor compound. IC50 value was determ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

LigandPNGBDBM12466(1-[(1-Adamantylamino)acetyl]-2-pyrrolidinecarbonit...)
Affinity DataIC50: 1.34E+5nMAssay Description:The DPP inhibition was measured by monitoring the cleavage of chromogenic substrate in the presence of each inhibitor compound. IC50 value was determ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Antwerp

LigandPNGBDBM12466(1-[(1-Adamantylamino)acetyl]-2-pyrrolidinecarbonit...)
Affinity DataIC50: 4nMAssay Description:Inhibition of DPP-4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed