BDBM19474 1-(4-chlorophenyl)-1H-imidazole::1-(4-chlorophenyl)imidazole::1-CPI::US11634391, Compound 149

SMILES Clc1ccc(cc1)-n1ccnc1

InChI Key InChIKey=BARLRKAYTDVUIS-UHFFFAOYSA-N

Data  1 IC50  2 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19474   

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandPNGBDBM19474(1-(4-chlorophenyl)-1H-imidazole | 1-(4-chloropheny...)
Affinity DataIC50: 5.16E+3nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
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Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 19474   

CellCytochrome P450 2B4(Rabbit)
Anhui Medical University

SyringePNGBDBM19474(1-(4-chlorophenyl)-1H-imidazole | 1-(4-chloropheny...)
ITC Data−TΔS°: 0.0997kcal/mole ΔH°: -8.14kcal/mole logk: 8.00E+5
pH: 7.4 T: 25.00°C 
In DepthDetails PubMed
CellCytochrome P450 2B4 Mutant (F206A)(Rabbit)
Anhui Medical University

SyringePNGBDBM19474(1-(4-chlorophenyl)-1H-imidazole | 1-(4-chloropheny...)
ITC Data−TΔS°: 3.30kcal/mole ΔH°: -10.9kcal/mole logk: 3.91E+5
pH: 7.4 T: 25.00°C 
In DepthDetails PubMed