BDBM50472784 METHYLLYCACONITINE[3H] MLA::[3H]-MLA

SMILES [H][C@]12C[C@]3([H])[C@]([H])([C@H]1OC)[C@](O)(C[C@@H]2OC)[C@]1(O)[C@@H](OC)[C@@]2([H])[C@@]33[C@H](CC[C@@]2(COC(=O)c2c([3H])cccc2N2C(=O)C[C@H](C)C2=O)CN(CC)[C@@]13[H])OC

InChI Key InChIKey=XLTANAWLDBYGFU-OAWTUDSLSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50472784   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50472784(METHYLLYCACONITINE[3H] MLA | [3H]-MLA)
Affinity DataKi:  0.980nMAssay Description:Inhibition of [3H]MLA binding in presence of methylcaconitine.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50472784(METHYLLYCACONITINE[3H] MLA | [3H]-MLA)
Affinity DataKi:  1.80nMAssay Description:Inhibition of [3H]MLA binding in presence of alpha-bungarotoxinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50472784(METHYLLYCACONITINE[3H] MLA | [3H]-MLA)
Affinity DataKi:  6.07E+3nMAssay Description:Inhibition of [3H]MLA binding in presence of (-)-nicotineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50472784(METHYLLYCACONITINE[3H] MLA | [3H]-MLA)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of [3H]MLA binding in presence of mecamylamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed