BDBM50024210 1H-indole-3-ethanamine::2-(1H-indol-3-yl)ethanamine::2-(3-indolyl)ethylamine::CHEMBL6640::tryptamine
SMILES NCCc1c[nH]c2ccccc12
InChI Key InChIKey=APJYDQYYACXCRM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 85 hits for monomerid = 50024210
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of cathepsin K by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataEC50: 716nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
Affinity DataEC50: 164nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.40nMAssay Description:Agonist activity at 5HT2A receptor (unknown origin) by cell based calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.30E+3nMAssay Description:Binding affinity to CYP2A6 (unknown origin) assessed as type 2 interaction as increase in absorbance 431 to 432 nm and decrease in 406 to 412 nmMore data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.20E+3nMAssay Description:Binding affinity to CYP2A13 (unknown origin) assessed as type 2 interaction as increase in absorbance 431 to 432 nm and decrease in 406 to 412 nmMore data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assayMore data for this Ligand-Target Pair
Affinity DataKd: 537nMAssay Description:The binding affinity to 5-hydroxytryptamine 2B receptor of rat fundusMore data for this Ligand-Target Pair
Affinity DataEC50: 310nMAssay Description:Agonist activity at rat N-terminal FLAG-tagged TAAR1 expressed in HEK293 cells assessed as [3H]cAMP accumulation measured after 1 hrMore data for this Ligand-Target Pair
Affinity DataEC50: 2.21E+3nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Guinea pig)
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataKi: 23nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1D receptor was determined in calf striatum homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor betaMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Evaluated for the binding affinity to porcine choroid plexus at 5-hydroxytryptamine 2C receptor binding site by using [3H]-MES as a radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 receptor binding site by using [3H]- DOB as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:In vitro affinity human cloned 5-hydroxytryptamine 1D receptor alpha by [3H]5-HT displacement.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Guinea pig)
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataKi: 70nMAssay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Displacement of [3H]5-HT from recombinant human 5-HT7 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Evaluated for the binding affinity to hippocampus striatal membranes at 5-hydroxytryptamine 1A receptor binding site by using [3H]-8-OH- DPAT as a ra...More data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Binding affinity for human 5-hydroxytryptamine 6 receptor expressed in HEK 293 human embryonic kidney cells, [3H]-lysergic acid diethylamide as radio...More data for this Ligand-Target Pair