BDBM50097125 2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid::2-hydroxy-5-{[4-(pyridin-2-ylsulfamoyl)phenyl]diazenyl}benzoic acid::4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene::5-((p-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid::5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid::5-(p-(2-Pyridylsulfamyl)phenylazo)salicylic acid::Salazosulfapyridine::Salicylazosulfapyridine::Sulfasalazine

SMILES OC(=O)c1cc(ccc1O)N=Nc1ccc(cc1)S(=O)(=O)Nc1ccccn1

InChI Key InChIKey=NCEXYHBECQHGNR-UHFFFAOYSA-N

Data  7 KI  6 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50097125   

TargetCarbonic anhydrase 1(Human)
Ataturk University

Curated by ChEMBL
LigandPNGBDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataIC50: 3.04E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

Curated by ChEMBL
LigandPNGBDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataIC50: 4.49E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFibroblast growth factor 1(Human)
Progen Industries

Curated by ChEMBL
LigandPNGBDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataKd:  6.09E+5nMAssay Description:Dissociation constant for Fibroblast growth factor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human liver OATP2B1 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E3S uptake incubated for 5 mins by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human liver OATP1B3 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E17-betaG uptake incubated for 5 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataIC50: 560nMAssay Description:Inhibition of human liver OATP1B1 expressed in HEK293 Flp-In cells assessed as reduction in E17-betaG uptake by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataKi:  530nMAssay Description:Inhibition of human liver OATP1B1 expressed in HEK293 Flp-In cells assessed as reduction in E17-betaG uptake by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of human liver OATP2B1 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E3S uptake incubated for 5 mins by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

Curated by ChEMBL
LigandPNGBDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataKi:  6.87E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 esterase activity by noncompetitive Lineweaver-Burke plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

Curated by ChEMBL
LigandPNGBDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataKi:  8.72E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 esterase activity by non-competitive Lineweaver-Burke plotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of human liver OATP1B3 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E17-betaG uptake incubated for 5 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed