BDBM50240898 5,7-Dihydroxy-3,6-dimethoxy-2-(4-methoxy-phenyl)-chromen-4-one::5,7-dihydroxy-3,6,4'-trimethoxyflavone::CHEMBL161957::SANTIN

SMILES COc1ccc(cc1)-c1oc2cc(O)c(OC)c(O)c2c(=O)c1OC

InChI Key InChIKey=DWZAJFZEYZIHPO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240898   

TargetXanthine dehydrogenase/oxidase(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50240898(CHEMBL161957 | 5,7-Dihydroxy-3,6-dimethoxy-2-(4-me...)
Affinity DataIC50: 3.65E+4nMAssay Description:Inhibition of xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Universidad Nacional De C£Rdoba

Curated by ChEMBL
LigandPNGBDBM50240898(CHEMBL161957 | 5,7-Dihydroxy-3,6-dimethoxy-2-(4-me...)
Affinity DataIC50: 220nMAssay Description:Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydroorotate dehydrogenase (fumarate)(Leishmania major)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50240898(CHEMBL161957 | 5,7-Dihydroxy-3,6-dimethoxy-2-(4-me...)
Affinity DataIC50: 2.62E+5nMAssay Description:Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydroorotate dehydrogenase (fumarate)(Leishmania major)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50240898(CHEMBL161957 | 5,7-Dihydroxy-3,6-dimethoxy-2-(4-me...)
Affinity DataIC50: 2.51E+5nMAssay Description:Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed