BDBM50123626 (S)-6-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL1303::Neupro::ROTIGOTINE
SMILES CCCN(CCc1cccs1)[C@H]1CCc2c(O)cccc2C1
InChI Key InChIKey=KFQYTPMOWPVWEJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50123626
Affinity DataEC50: 0.700nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHO cells assessed as increase of forskolin-induced cAMP production after 20 minsMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 3.20nMAssay Description:Agonist activity at human D2S receptor expressed in HEK293T cell membranes coexpressing Galphao1 assessed as induction of nucleotide exchange preincu...More data for this Ligand-Target Pair
Affinity DataEC50: 4.10nMAssay Description:Partial agonist activity at human D2SR expressed in HEK293T cells co-expressing (EA)beta-arrestin2 assessed as induction of beta-arrestin2 recruitmen...More data for this Ligand-Target Pair
Affinity DataEC50: 4.40nMAssay Description:Partial agonist activity at human D2SR expressed in HEK293T cells co-expressing (EA)beta-arrestin2 and GRK2 assessed as induction of beta-arrestin2 r...More data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]N-0437 binding on Dopamine receptor D2L of CHO K-1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:In vitro binding affinity at human Dopamine receptor D2 expressed in CHO K1 cells was measured by its ability to displace [3H]- N-0437More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:In vitro binding affinity at human Dopamine receptor D3 expressed in CHO K1 cells was measured by its ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity of compound for Dopamine receptor D2 using [3H]N-0437More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D2L of CHO K-1 cells.More data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D4.2 of CHO K-1 cells.More data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Binding affinity of compound for Dopamine receptor D1 using [3H]-SCH- 23390More data for this Ligand-Target Pair