BDBM50015094 CHEMBL152665::N-Hydroxy-2-phenyl-acetamide::N-hydroxy-2-phenylacetamide::Phenylacetohydroxamic acid

SMILES ONC(=O)Cc1ccccc1

InChI Key InChIKey=FPOQLQZHRCEVOT-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50015094   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015094(CHEMBL152665 | N-hydroxy-2-phenylacetamide | N-Hyd...)
Affinity DataIC50: 3.00E+5nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015094(CHEMBL152665 | N-hydroxy-2-phenylacetamide | N-Hyd...)
Affinity DataIC50: 3.00E+5nMAssay Description:Compound was tested for its in vitro inhibitory activity against RBL-1 5-LO (time dependent)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 4(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50015094(CHEMBL152665 | N-hydroxy-2-phenylacetamide | N-Hyd...)
Affinity DataIC50: 3.33E+4nMT: 2°CAssay Description:Inhibition of HDAC4 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50015094(CHEMBL152665 | N-hydroxy-2-phenylacetamide | N-Hyd...)
Affinity DataIC50: 3.33E+4nMT: 2°CAssay Description:Inhibition of HDAC2 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50015094(CHEMBL152665 | N-hydroxy-2-phenylacetamide | N-Hyd...)
Affinity DataIC50: 1.16E+4nMT: 2°CAssay Description:Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50015094(CHEMBL152665 | N-hydroxy-2-phenylacetamide | N-Hyd...)
Affinity DataIC50: 1.10E+3nMT: 2°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015094(CHEMBL152665 | N-hydroxy-2-phenylacetamide | N-Hyd...)
Affinity DataIC50: 158nMAssay Description:Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetElastase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50015094(CHEMBL152665 | N-hydroxy-2-phenylacetamide | N-Hyd...)
Affinity DataIC50: 1.36E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed