BDBM50346422 10-(3-(4-hydroxypiperidin-1-yl)propyl)-10H-phenothiazine-2-carbonitrile::CHEMBL251940::PROPERICIAZINE::periciazine

SMILES OC1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C#N)CC1

InChI Key InChIKey=LUALIOATIOESLM-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50346422   

TargetCholinesterase(Horse)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50346422(CHEMBL251940 | periciazine | PROPERICIAZINE | 10-(...)
Affinity DataIC50: 230nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocholine iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Bovine)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50346422(CHEMBL251940 | periciazine | PROPERICIAZINE | 10-(...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of bovine erythrocyte AChE using acetylthiocholine iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Janssen Pharmaceutica

Curated by PDSP Ki Database
LigandPNGBDBM50346422(CHEMBL251940 | periciazine | PROPERICIAZINE | 10-(...)
Affinity DataKi:  4.10nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2C adrenergic receptor(Rat)
Janssen Pharmaceutica

Curated by PDSP Ki Database
LigandPNGBDBM50346422(CHEMBL251940 | periciazine | PROPERICIAZINE | 10-(...)
Affinity DataKi:  160nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2C adrenergic receptor(Rat)
Janssen Pharmaceutica

Curated by PDSP Ki Database
LigandPNGBDBM50346422(CHEMBL251940 | periciazine | PROPERICIAZINE | 10-(...)
Affinity DataKi:  220nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2C adrenergic receptor(Rat)
Janssen Pharmaceutica

Curated by PDSP Ki Database
LigandPNGBDBM50346422(CHEMBL251940 | periciazine | PROPERICIAZINE | 10-(...)
Affinity DataKi:  2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAndrogen receptor(Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50346422(CHEMBL251940 | periciazine | PROPERICIAZINE | 10-(...)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [3H]mibolerone from rat androgen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2C adrenergic receptor(Rat)
Janssen Pharmaceutica

Curated by PDSP Ki Database
LigandPNGBDBM50346422(CHEMBL251940 | periciazine | PROPERICIAZINE | 10-(...)
Affinity DataKi:  3.20E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed