BDBM45440 4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydroxyethanesulfonic acid::4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarboximidamide;2-hydroxyethanesulfonic acid::4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarboximidamide;2-oxidanylethanesulfonic acid::CHEMBL494163::MLS000028738::PENTAMIDINE::PENTAMIDINE ISETHIONATE::SMR000059147::cid_359323
SMILES NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(N)=N)cc1
InChI Key InChIKey=XDRYMKDFEDOLFX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 64 hits for monomerid = 45440
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of Escherichia coli GroEL/GroES-ATPase activity expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human microsomal CYP1A2 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Modena and Reggio Emilia
Curated by ChEMBL
University of Modena and Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of human ERG incubated for 2 hrs by fluorescence polarisation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human microsomal CYP2C19 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.48E+4nMAssay Description:Inhibition of human microsomal CYP2D6 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human microsomal CYP3A4 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full-length human aurora B kinase expressed in baculovirus system using MBP as substrate incubated for 45 mins by ADP-glo k...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human microsomal CYP2C9 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human mitochondrial HSP60/HSP10 expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH refolding pre...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human mitochondrial HSP60/HSP10-ATPase activity expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured M...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2C9 expressed in baculovirus-infected insect cells using Luciferin-H as substrate in presence of NADPH by P450-Glo luminescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Escherichia coli GroEL/GroES expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH refolding preinc...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP3A4 expressed in baculovirus infected insect cells using beetle D-luciferin as substrate preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP2C9 expressed in baculovirus infected insect cells using beetle D-luciferin as substrate preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2D6 expressed in baculovirus infected insect cells using beetle D-luciferin as substrate preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Modena and Reggio Emilia
Curated by ChEMBL
University of Modena and Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of Tracer Red from human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP1A2 expressed in baculovirus infected insect cells using beetle D-luciferin as substrate preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP2C19 expressed in baculovirus infected insect cells using beetle D-luciferin as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human plasmin assessed as reduction in protein-mediated thrombin-induced fibrin rich clot lysis measured over 5 to 100 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Direct inhibition of human plasmin preincubated for 10 mins followed by spectrozyme PL additionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of human factor 10a preincubated for 10 mins followed by spectrozyme FXa additionMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of PTP4A1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of PTP4A3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of PTP4A2 (unknown origin)More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 1(Human)
Csir-Indian Institute of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of TMPRSS2 (247 to 492 residues) (unknown origin) peptidase domain expressed in Escherichia coli BL21 (DE3) incubated for 30 mins followed...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP3A4 expressed in baculovirus-infected insect cells using Luciferin-PFBE as substrate in presence of NADPH by P450-Glo luminesc...More data for this Ligand-Target Pair
Affinity DataEC50: 2.79E+4nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Quantities of 0.2 mL of examined preparation (as control, 0.15 M NaCl), buffer, and 0.1 mL of enzyme solution were mixed together. The mixture was in...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Quantities of 0.2 mL of examined preparation (as control, 0.15 M NaCl), buffer, and 0.1 mL of enzyme solution were mixed together. The mixture was in...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Quantities of 0.2 mL of examined preparation (as control, 0.15 M NaCl), buffer, and 0.1 mL of enzyme solution were mixed together. The mixture was in...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Xavier University of Louisiana
Curated by ChEMBL
Xavier University of Louisiana
Curated by ChEMBL
Affinity DataIC50: 720nMpH: 7.6Assay Description:Antagonist activity at NR1/NR2A receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced cur...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Binding to holo-S100B proteinMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 5.36E+4nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
Affinity DataIC50: 5.36E+4nMAssay Description:Inhibition of human PRL3 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Affinity DataKd: 4.40E+4nMAssay Description:Binding affinity to recombinant rat calcium loaded S100-B by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 5.00E+4nMAssay Description:Binding affinity to recombinant rat calcium loaded S100-B by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibition of rabbit muscle GAPDH.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human S100B/human TAMRA-p53(367-388) interaction by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Modena and Reggio Emilia
Curated by ChEMBL
University of Modena and Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of human ERG by Tracer Red dye based fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.48E+4nMAssay Description:Inhibition of human CYP2D6 expressed in baculovirus-infected insect cells using Luciferin-ME EGE as substrate in presence of NADPH by P450-Glo lumine...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2C19 expressed in baculovirus-infected insect cells using Luciferin-H EGE as substrate in presence of NADPH by P450-Glo lumine...More data for this Ligand-Target Pair