BDBM50210804 2-Amino-9-(4-hydroxy-3-hydroxymethyl-butyl)-1,9-dihydro-purin-6-one::2-Amino-9-(4-hydroxy-3-hydroxymethyl-butyl)-1,9-dihydro-purin-6-one (PCV)::2-Amino-9-(4-hydroxy-3-hydroxymethyl-butyl)-1,9-dihydro-purin-6-one(PCV, Penciclovir)::2-[2-(2-Amino-6-hydroxy-purin-9-yl)-ethyl]-propane-1,3-diol::9-(4-HYDROXY-3-(HYDROXYMETHYL)BUT-1-YL)GUANINE::BRL-39123::CHEMBL1540::PENCICLOVIR::pencyclovir

SMILES Nc1nc2n(CCC(CO)CO)cnc2c(=O)[nH]1

InChI Key InChIKey=JNTOCHDNEULJHD-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50210804   

TargetThymidine kinase(HHV-1)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50210804(CHEMBL1540 | 2-Amino-9-(4-hydroxy-3-hydroxymethyl-...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetThymidine kinase(CeHV-1)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50210804(CHEMBL1540 | 2-Amino-9-(4-hydroxy-3-hydroxymethyl-...)
Affinity DataIC50: 8.44E+4nMAssay Description:Inhibition of Herpes B virus recombinant thymidine kinase-mediated [3H]TdR phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed