BDBM50371229 Livalo::PITAVASTATIN CALCIUM::cid_24848419

SMILES O[C@H](C[C@H](O)\C=C\c1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC([O-])=O

InChI Key InChIKey=VGYFMXBACGZSIL-UHFFFAOYSA-M

Data  2 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50371229   

TargetCystic fibrosis transmembrane conductance regulator(Human)
Southern Research Institute

Curated by PubChem BioAssay
LigandPNGBDBM50371229(Livalo | PITAVASTATIN CALCIUM | cid_24848419)
Affinity DataEC50: >5.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50371229(Livalo | PITAVASTATIN CALCIUM | cid_24848419)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of Holtzman-Sprague-Dawley rat liver HMG CoA reductase after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50371229(Livalo | PITAVASTATIN CALCIUM | cid_24848419)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Xiamen University

Curated by ChEMBL
LigandPNGBDBM50371229(Livalo | PITAVASTATIN CALCIUM | cid_24848419)
Affinity DataKd:  1.33E+4nMAssay Description:Binding affinity to RXRalpha-LBD (unknown origin) measured up to 120 sec by surface plasma resonance methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed