BDBM50422542 Keppra::Keppra Xr::LEVETIRACETAM::Levetiracetam In Sodium Chloride::UCB-22059::UCB-L059

SMILES CC[C@H](N1CCCC1=O)C(N)=O

InChI Key InChIKey=HPHUVLMMVZITSG-UHFFFAOYSA-N

Data  6 IC50

PDB links: 4 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50422542   

TargetSynaptic vesicle glycoprotein 2A(Rat)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataIC50: 794nMAssay Description:In vitro inhibitory activity against [3H](2S)-2-[4-(3-azidophenyl)-2-oxopyrrolidin-1-yl]butanamide binding to levetiracetam binding siteMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50422542(UCB-22059 | UCB-L059 | Keppra | Keppra Xr | Leveti...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed