BDBM50022772 CHEMBL1025::Diisopropoxyphosphoryl fluoride::Diisopropyl fluorophosphonate::Diisopropyl phosphofluoridate::Diisopropyl phosphorofluoridate::Diisopropylfluorophosphate::Diisopropylfluorophosphoric acid ester::Diisopropylphosphorofluoridate::Fluorodiisopropyl phosphate::ISOFLUROPHATE::Isofluorphate::Isoflurophosphate::Isopropyl fluophosphate::Isopropyl phosphorofluoridate::Neoglaucit::O,O'-Diisopropyl phosphoryl fluoride::bis(propan-2-yl) fluorophosphate::diisopropyl fluorophosphate

SMILES CC(C)OP(F)(=O)OC(C)C

InChI Key InChIKey=MUCZHBLJLSDCSD-UHFFFAOYSA-N

Data  8 KI  4 IC50  2 Kd  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50022772   

TargetAcetylcholinesterase(Electric eel)
Niddk

Curated by ChEMBL
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataIC50: 480nMAssay Description:In vitro inhibitory activity against acetylcholinesterase from electric eelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataKoff:  2.17E+3s-1Assay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLiver carboxylesterase(Pig)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of porcine liver carboxylesterase using [14C]GS-7340 substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysosomal protective protein(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant CatA using [14C]GS-7340 substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataKd:  7.00E+4nMAssay Description:Inhibition of Torpedo californica AChEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to human AChEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataKi:  170nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataKi:  760nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of human AChE assessed as equilibrium binding by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
Georgetown University

Curated by PDSP Ki Database
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
Georgetown University

Curated by PDSP Ki Database
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
Georgetown University

Curated by PDSP Ki Database
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
Georgetown University

Curated by PDSP Ki Database
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM50022772(Isopropyl phosphorofluoridate | Neoglaucit | O,O'-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed