BDBM28803 2-[4-(4-chlorophenoxy)phenoxy]propanoic acid::Clofop::Fenofibric acid::HCG 004

SMILES CC(Oc1ccc(Oc2ccc(Cl)cc2)cc1)C(O)=O

InChI Key InChIKey=BSFAVVHPEZCASB-UHFFFAOYSA-N

Data  2 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 28803   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM28803(Clofop | HCG 004 | 2-[4-(4-chlorophenoxy)phenoxy]p...)
Affinity DataIC50: 9.84E+4nM EC50:  1.16E+4nMpH: 8.0 T: 2°CAssay Description:For hPPAR alpha, percentage inhibition was calculated relative to unlabeled GW2331, which was used as the active site-specific competitive binder. Fl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb

LigandPNGBDBM28803(Clofop | HCG 004 | 2-[4-(4-chlorophenoxy)phenoxy]p...)
Affinity DataIC50: 9.84E+4nM EC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:For PPARgamma, the percentage inhibition was calculated relative to rosiglitazone, which was used as the active site-specific competitive binder. Flu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Golden hamster)
Bristol-Myers Squibb

LigandPNGBDBM28803(Clofop | HCG 004 | 2-[4-(4-chlorophenoxy)phenoxy]p...)
Affinity DataEC50:  2.87E+4nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Bristol-Myers Squibb

LigandPNGBDBM28803(Clofop | HCG 004 | 2-[4-(4-chlorophenoxy)phenoxy]p...)
Affinity DataEC50:  1.85E+4nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28803(Clofop | HCG 004 | 2-[4-(4-chlorophenoxy)phenoxy]p...)
Affinity DataEC50:  1.77E+4nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed