BDBM50009834 2-Propylvaleric acid sodium salt::CHEMBL433::Depakene::Depakote::Divalproex::Divalproex sodium::Epilim::VALPROATE SODIUM::sodium 2-propylpentanoate::sodium valproate

SMILES CCCC(CCC)C([O-])=O

InChI Key InChIKey=NIJJYAXOARWZEE-UHFFFAOYSA-M

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50009834   

TargetHistone deacetylase 2b(Maize)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50009834(sodium valproate | CHEMBL433 | Epilim | sodium 2-p...)
Affinity DataIC50: 1.28E+5nMAssay Description:Concentration required for inhibition of histone deacetylase HD2 in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50009834(sodium valproate | CHEMBL433 | Epilim | sodium 2-p...)
Affinity DataIC50: 3.80E+5nMAssay Description:Inhibitory activity measured against rat lens aldose reductase using 3-pyridinecarboxaldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50009834(sodium valproate | CHEMBL433 | Epilim | sodium 2-p...)
Affinity DataIC50: 8.90E+4nMAssay Description:Selectivity ratio measured as the IC50 ratio of aldehyde/aldose reductase valuesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2b(Maize)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50009834(sodium valproate | CHEMBL433 | Epilim | sodium 2-p...)
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50009834(sodium valproate | CHEMBL433 | Epilim | sodium 2-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human LTA4H aminopeptidase activity expressed in Escherichia coli BL21 (DE3) pLysS assessed as formation of p-NA from Ala-p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50009834(sodium valproate | CHEMBL433 | Epilim | sodium 2-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human LTA4H Epoxide Hydrolase expressed in Escherichia coli BL21 (DE3) pLysS preincubated for 10 mins followed by addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed