BDBM50404252 BMY-40900::DDI::DIDANOSINE

SMILES OC[C@@H]1CC[C@@H](O1)n1cnc2c1nc[nH]c2=O

InChI Key InChIKey=BXZVVICBKDXVGW-UHFFFAOYSA-N

Data  6 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50404252   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50404252(BMY-40900 | DDI | DIDANOSINE)
Affinity DataIC50: 7.15E+3nMAssay Description:Inhibitory concentration against SO561945 (HIV 1 mutant RT) viral infection of MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlbumin(Human)
Mercer University

Curated by ChEMBL
LigandPNGBDBM50404252(BMY-40900 | DDI | DIDANOSINE)
Affinity DataKd:  4.40E+4nMAssay Description:Binding affinity to human serum albumin with excitation at 280 nm after 2 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50404252(BMY-40900 | DDI | DIDANOSINE)
Affinity DataIC50: 5.37E+3nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50404252(BMY-40900 | DDI | DIDANOSINE)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50404252(BMY-40900 | DDI | DIDANOSINE)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50404252(BMY-40900 | DDI | DIDANOSINE)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50404252(BMY-40900 | DDI | DIDANOSINE)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed