BDBM22726 Benzophenone::CHEMBL90039::diphenylmethanone

SMILES O=C(c1ccccc1)c1ccccc1

InChI Key InChIKey=RWCCWEUUXYIKHB-UHFFFAOYSA-N

Data  5 KI  4 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 22726   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM22726(diphenylmethanone | CHEMBL90039 | Benzophenone)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPapain(Papaya)
Federal University of Alfenas

Curated by ChEMBL
LigandPNGBDBM22726(diphenylmethanone | CHEMBL90039 | Benzophenone)
Affinity DataIC50: 3.47E+6nMAssay Description:Inhibition of Carica papaya papain by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin B(Human)
Federal University of Alfenas

Curated by ChEMBL
LigandPNGBDBM22726(diphenylmethanone | CHEMBL90039 | Benzophenone)
Affinity DataIC50: 2.89E+5nMAssay Description:Inhibition of cathepsin B by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAndrogen receptor(Rat)
University of Basel

Curated by ChEMBL
LigandPNGBDBM22726(diphenylmethanone | CHEMBL90039 | Benzophenone)
Affinity DataIC50: 1.29E+5nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor XII(Human)
University of Mississippi

LigandPNGBDBM22726(diphenylmethanone | CHEMBL90039 | Benzophenone)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.45kcal/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLiver carboxylesterase 1(Human)
University of Mississippi

LigandPNGBDBM22726(diphenylmethanone | CHEMBL90039 | Benzophenone)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLiver carboxylesterase 1(Rabbit)
University of Mississippi

LigandPNGBDBM22726(diphenylmethanone | CHEMBL90039 | Benzophenone)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Mississippi

LigandPNGBDBM22726(diphenylmethanone | CHEMBL90039 | Benzophenone)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Mississippi

LigandPNGBDBM22726(diphenylmethanone | CHEMBL90039 | Benzophenone)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed