BDBM22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244
SMILES CC(=O)Oc1ccccc1C(O)=O
InChI Key InChIKey=BSYNRYMUTXBXSQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 127 hits for monomerid = 22360
Affinity DataIC50: 350nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMpH: 8.0Assay Description:Approximately 2 µg of either COX-1 or COX-2 was added to buffer containing 100 µM AA, 0.1 M Tris-HCl buffer (pH 8.0), 5 mM EDTA, 2 mM phenol, and 1 µ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+5nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 isolated from ram (sheep) seminal vesicleMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+5nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 2 obtained from sheep placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibitory concentration in DMSO with purified ovine Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibitory concentration in DMSO with purified human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Human)
Department of Horticulture and National Food Safety and Toxicology Center
Curated by ChEMBL
Department of Horticulture and National Food Safety and Toxicology Center
Curated by ChEMBL
Affinity DataIC50: 1.05E+6nMAssay Description:Inhibition of PGHS1 assessed as conversion of arachidonic acid to prostaglandinMore data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+6nMAssay Description:Inhibition of PGHS2 assessed as conversion of arachidonic acid to prostaglandinMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Human)
Department of Horticulture and National Food Safety and Toxicology Center
Curated by ChEMBL
Department of Horticulture and National Food Safety and Toxicology Center
Curated by ChEMBL
Affinity DataIC50: 7.80E+5nMAssay Description:Inhibition of COX1 by scintillation proximity assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Human)
Department of Horticulture and National Food Safety and Toxicology Center
Curated by ChEMBL
Department of Horticulture and National Food Safety and Toxicology Center
Curated by ChEMBL
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of COX1 by radioimmunoassay methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Human)
Department of Horticulture and National Food Safety and Toxicology Center
Curated by ChEMBL
Department of Horticulture and National Food Safety and Toxicology Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:In vitro inhibition of ovine prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:In vitro inhibition of ovine prostaglandin G/H synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:In vitro inhibitory concentration against COX-1 enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:In vitro inhibitory concentration against COX-2 enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibition of COX2 by radioimmunoassay methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of ovine COX2 by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of ovine COX2 by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of ovine COX1 by measuring PGE2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant COX2 by measuring PGE2More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of gamma-glutamyltranspeptidase by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of ovine COX2 by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of ovine COX2 by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.71E+6nMAssay Description:Inhibition of human carbonic anhydrase 1 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+6nMAssay Description:Inhibition of human carbonic anhydrase 2 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of ovine COX2 by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of ovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of ovine COX2 by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGF2-alpha formation using arachidonic acid as substrate by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.88E+7nMAssay Description:Inhibition of COX1 from ram seminal vesicles by liquid scintillation counterMore data for this Ligand-Target Pair