BDBM85213 Agmatine::CAS_306-60-5::CHEMBL58343::NSC_199::US8633208, Agmatine

SMILES [#7]-[#6]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7]

InChI Key InChIKey=XWVGKWZOVAVNBI-UHFFFAOYSA-N

Data  6 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 85213   

TargetAmine oxidase [flavin-containing] A(Human)
Rottapharm

US Patent
LigandPNGBDBM85213(CHEMBL58343 | US8633208, Agmatine | NSC_199 | CAS_...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Rottapharm

US Patent
LigandPNGBDBM85213(CHEMBL58343 | US8633208, Agmatine | NSC_199 | CAS_...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDeoxyhypusine synthase(Rat)
National Institute of Dental Research

Curated by ChEMBL
LigandPNGBDBM85213(CHEMBL58343 | US8633208, Agmatine | NSC_199 | CAS_...)
Affinity DataIC50: 1.56E+5nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNischarin(Rat)
Gda£?Sk University of Technology

Curated by ChEMBL
LigandPNGBDBM85213(CHEMBL58343 | US8633208, Agmatine | NSC_199 | CAS_...)
Affinity DataIC50: 3.65E+4nMAssay Description:Displacement of [3H]clonidine from imidazoline I1 receptor in Wistar rat kidney by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNischarin(Rat)
Gda£?Sk University of Technology

Curated by ChEMBL
LigandPNGBDBM85213(CHEMBL58343 | US8633208, Agmatine | NSC_199 | CAS_...)
Affinity DataIC50: 3.65E+4nMAssay Description:Inhibition of Wistar rat imidazoline I1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine oxidase 1(Maize)
University of Siena

Curated by ChEMBL
LigandPNGBDBM85213(CHEMBL58343 | US8633208, Agmatine | NSC_199 | CAS_...)
Affinity DataKi:  3.00E+3nMpH: 6.5Assay Description:Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNischarin(Rat)
Gda£?Sk University of Technology

Curated by ChEMBL
LigandPNGBDBM85213(CHEMBL58343 | US8633208, Agmatine | NSC_199 | CAS_...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNischarin(Rat)
Gda£?Sk University of Technology

Curated by ChEMBL
LigandPNGBDBM85213(CHEMBL58343 | US8633208, Agmatine | NSC_199 | CAS_...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetIonotropic glutamate receptor subunit Delta2(African clawed frog)
State University of New York

Curated by PDSP Ki Database
LigandPNGBDBM85213(CHEMBL58343 | US8633208, Agmatine | NSC_199 | CAS_...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
University of Cologne

Curated by ChEMBL
LigandPNGBDBM85213(CHEMBL58343 | US8633208, Agmatine | NSC_199 | CAS_...)
Affinity DataKi:  8.60E+6nMAssay Description:TP_TRANSPORTER: inhibition of uptake of 0.1 uM MPP+ in OCT1-expressing 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 1(Human)
University of Cologne

Curated by ChEMBL
LigandPNGBDBM85213(CHEMBL58343 | US8633208, Agmatine | NSC_199 | CAS_...)
Affinity DataKi:  2.40E+7nMAssay Description:TP_TRANSPORTER: inhibition of uptake of 0.1 uM MPP+ in OCT1-expressing 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed