BDBM25755 Acebutolol::Acetobutolol::N-{3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}butanamide::Neptal

SMILES CCCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(c1)C(C)=O

InChI Key InChIKey=GOEMGAFJFRBGGG-UHFFFAOYSA-N

Data  4 KI  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 25755   

TargetBeta-1 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25755(N-{3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propo...)
Affinity DataKd:  347nMpH: 7.4 T: 2°CAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25755(N-{3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propo...)
Affinity DataKd:  832nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25755(N-{3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propo...)
Affinity DataKd:  3.89E+4nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
Niigata College of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM25755(N-{3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propo...)
Affinity DataKi:  126nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-2 adrenergic receptor(Rat)
Niigata College of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM25755(N-{3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propo...)
Affinity DataKi:  7.08E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Lausanne

Curated by ChEMBL
LigandPNGBDBM25755(N-{3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propo...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM25755(N-{3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propo...)
Affinity DataKi:  9.58E+4nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in OCT1-expressing HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed