BDBM7262 14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaen-9-one::9-Nitropaullone::BDBM84528::CHEMBL50894::NSC 705701::Paullone Analog 1::alsterpaullone
SMILES [O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1
InChI Key InChIKey=OLUKILHGKRVDCT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 52 hits for monomerid = 7262
TargetMitogen-activated protein kinase 1(Human)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Erk2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of GSK3beta (unknown origin) expressed in Sf9 cells using GS1 as substrate and [gamma32]ATP after 30 min by scinitllation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human GSK-3beta incubated with substrate in presence of ATP measured by serial dilution assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human GSK-3beta preincubated for 3 hrs followed by ATP and substrate addition measured by serial dilution assayMore data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Csir-Indian Institute of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of SARS-CoV-2 M-proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of GSK-3beta (unknown origin) expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin) in presence of gamma32P-ATP by scintillation counter analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Human)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of Erk1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Human)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of Erk1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human GSK-3beta using YRRAAVPPSPSLSRHSSPHQS(p) EDEEE substrate peptide and [gamma-33P-ATP] incubated for 40 mins by scintillation count...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Human)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of Erk2 (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Protein kinase C (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CK1 (unknown origin)More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Human)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Raf (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Human)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of GSK3alpha (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Jun NH2-terminal kinase (unknown origin)More data for this Ligand-Target Pair
TargetInsulin receptor(Human)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Insulin receptor tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Rat)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant recombinant rat GSK3beta using GS-1 peptide as substrate in presence of [gamma-32P]ATP measured after 30 mins incubation by...More data for this Ligand-Target Pair
TargetMO15-related protein kinase Pfmrk(malaria parasite P. falciparum)
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibitory activity against Plasmodium falciparum cyclin dependent protein kinase, PfmrkMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Rat)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 4nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
Affinity DataIC50: 35nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:In vitro inhibitory activity against cyclin-dependent kinase 1-cyclin B (Cyclin-Dependent Kinase) harvested from starfish oocytes.More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of glycogen synthase kinase-3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of CDK5/p25 (unknown origin) after 30 mins by SDS-PAGE analysisMore data for this Ligand-Target Pair
TargetMO15-related protein kinase Pfmrk(malaria parasite P. falciparum)
Institute of Research
Curated by ChEMBL
Institute of Research
Curated by ChEMBL
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of Plasmodium falciparum cyclin-dependent kinaseMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Human)
Technische Universit£T Braunschweig
Curated by ChEMBL
Technische Universit£T Braunschweig
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK1/cyclin B expressed in M phase starfish oocyteMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of GSK3-beta expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant GSK3betaMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Human)
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research (NIPER)
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of GSK3alphaMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Human)
Technische Universit£T Braunschweig
Curated by ChEMBL
Technische Universit£T Braunschweig
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair