BDBM11940 2-AMP::2-Adenylic acid::Adenosine 2-monophosphate::{[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1OP(O)(O)=O

InChI Key InChIKey=QDFHPFSBQFLLSW-UHFFFAOYSA-N

Data  1 IC50  1 EC50  1 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11940   

TargetInositol monophosphatase 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM11940({[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydrox...)
Affinity DataIC50: 1.30E+6nMAssay Description:Tested for the inhibitory activity against bovine inositol monophosphatase by measuring concentration inhibiting the production of [14C]inositol from...More data for this Ligand-Target Pair
In DepthDetails Article

TargetAdenosine receptor A1(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM11940({[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydrox...)
Affinity DataEC50:  490nMAssay Description:Agonist activity at human A1AR expressed in HEK293T/17 cells assessed as inhibition of isoproterenol-induced cAMP accumulation incubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 11940   

CellCytochrome P450 Reductase (CPR)(Human)
Merck Research Laboratories

SyringePNGBDBM11940({[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydrox...)
ITC DataΔG°: -6.99kcal/mole −TΔS°: 6.89kcal/mole ΔH°: -14.0kcal/mole logk: 4.70E+5
pH: 7.0 T: 25.00°C