PMID

Data

Article Title

Organization

Protected aminooxyprolines for expedited library synthesis: application to Tsg101-directed proline-oxime containing peptides.

Nih

New HIV-1 reverse transcriptase inhibitors based on a tricyclic benzothiophene scaffold: synthesis, resolution, and inhibitory activity.

Nih

Application of azide-alkyne cycloaddition 'click chemistry' for the synthesis of Grb2 SH2 domain-binding macrocycles.

Nih

Synthesis of tripeptides as potent Yersinia protein tyrosine phosphatase inhibitors.

Nih

Utilization of a nitrobenzoxadiazole (NBD) fluorophore in the design of a Grb2 SH2 domain-binding peptide mimetic.

Nih

Design and synthesis of dimeric HIV-1 integrase inhibitory peptides.

Nih

Acylsulfonamide-containing PTP1B inhibitors designed to mimic an enzyme-bound water of hydration.

Nih

Bicyclic-fused heteroaryl or aryl compounds

Pfizer

Substituted pyrrolidines as mGluR5 antagonists

Hua Medicine (Shanghai)

NMDA receptor modulators and uses related thereto

Emory University

Compounds antagonizing A3 adenosine receptor, method for preparing them, and medical-use thereof

Handok

4,6-substituted-pyrazolo[1,5-a]pyrazines as janus kinase inhibitors

Array Biopharma

HIV-1 reverse transcriptase structure with RNase H inhibitor dihydroxy benzoyl naphthyl hydrazone bound at a novel site.

Rutgers University

Discovery of 2-[4-{{2-(2S,5R)-2-cyano-5-ethynyl-1-pyrrolidinyl]-2-oxoethyl]amino]-4-methyl-1-piperidinyl]-4-pyridinecarboxylic acid (ABT-279): a very potent, selective, effective, and well-tolerated inhibitor of dipeptidyl peptidase-IV, useful for the treatment of diabetes.

Abbott Laboratories

Improved P1/P1' substituents for cyclic urea based HIV-1 protease inhibitors: synthesis, structure-activity relationship, and X-ray crystal structure analysis.

Dupont Pharmaceuticals

Indenopyrazoles as novel cyclin dependent kinase (CDK) inhibitors.

Dupont Pharmaceuticals