The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.0M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 695K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Advanced Search

35 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Design, synthesis and evaluation of antiproliferative activity of melanoma-targeted histone deacetylase inhibitors.EBI
Georgia Institute of Technology
Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase.EBI
Georgia Institute of Technology
Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions.EBI
Georgia Institute of Technology
Design and structure activity relationship of tumor-homing histone deacetylase inhibitors conjugated to folic and pteroic acids.EBI
Georgia Institute of Technology
The antileishmanial activity of isoforms 6- and 8-selective histone deacetylase inhibitors.EBI
Georgia Institute of Technology
3-Hydroxypyridin-2-thione as novel zinc binding group for selective histone deacetylase inhibition.EBI
Georgia Institute of Technology
Dual targeting of histone deacetylase and topoisomerase II with novel bifunctional inhibitors.EBI
Georgia Institute of Technology
Design and synthesis of novel histone deacetylase inhibitor derived from nuclear localization signal peptide.EBI
Georgia Institute of Technology
Aza-peptidyl Michael acceptor and epoxide inhibitors--potent and selective inhibitors of Schistosoma mansoni and Ixodes ricinus legumains (asparaginyl endopeptidases).EBI
Georgia Institute of Technology
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: restricted rotation analogues of methylphenidate.EBI
Georgia Institute of Technology
Synthesis and pharmacology of site specific cocaine abuse treatment agents: 8-substituted isotropane (3-azabicyclo[3.2.1]octane) dopamine uptake inhibitors.EBI
Georgia Institute of Technology
Syntheses and biological activities of a novel group of steroidal derived inhibitors for human Cdc25A protein phosphatase.EBI
Georgia Institute of Technology
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-(aminomethyl)-3-phenylbicyclo[2.2.2]- and -[2.2.1]alkane dopamine uptake inhibitors.EBI
Georgia Institute of Technology
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-substituted-6-amino-5-phenylbicyclo[2.2.2]octanes.EBI
Georgia Institute of Technology
Synthesis and pharmacology of potential cocaine antagonists. 2. Structure-activity relationship studies of aromatic ring-substituted methylphenidate analogs.EBI
Georgia Institute of Technology
Novel anthraquinone inhibitors of human leukocyte elastase and cathepsin G.EBI
Georgia Institute of Technology
Unexpected inhibition of S-adenosyl-L-homocysteine hydrolase by a guanosine nucleoside.EBI
Georgia Institute of Technology
Peptidyl alpha-ketoamides with nucleobases, methylpiperazine, and dimethylaminoalkyl substituents as calpain inhibitors.EBI
Georgia Institute of Technology
Non-peptide macrocyclic histone deacetylase inhibitors derived from tricyclic ketolide skeleton.EBI
Georgia Institute of Technology
Synthetic methodology-enabled discovery of a tunable indole template for COX-1 inhibition and anti-cancer activity.EBI
Georgia Institute of Technology
Pyrimethamine conjugated histone deacetylase inhibitors: Design, synthesis and evidence for triple negative breast cancer selective cytotoxicity.EBI
Georgia Institute of Technology
Novel small molecule binders of human N-glycanase 1, a key player in the endoplasmic reticulum associated degradation pathway.EBI
Georgia Institute of Technology
Novel peptidyl alpha-keto amide inhibitors of calpains and other cysteine proteases.EBI
Georgia Institute of Technology
A structure-activity relationship of non-peptide macrocyclic histone deacetylase inhibitors and their anti-proliferative and anti-inflammatory activities.EBI
Georgia Institute of Technology
Ligand binding studies, preliminary structure-activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inhibitors of Escherichia coli dihydrofolate reductase.EBI
Georgia Institute of Technology
Synthesis and structure-activity relationship of 3-hydroxypyridine-2-thione-based histone deacetylase inhibitors.EBI
Georgia Institute of Technology
Peptide alpha-keto ester, alpha-keto amide, and alpha-keto acid inhibitors of calpains and other cysteine proteases.EBI
Georgia Institute of Technology
Histone deacetylase inhibitors equipped with estrogen receptor modulation activity.EBI
Georgia Institute of Technology
Dual-acting histone deacetylase-topoisomerase I inhibitors.EBI
Georgia Institute of Technology
Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group.EBI
Georgia Institute of Technology
Synthesis and structure-activity relationship of histone deacetylase (HDAC) inhibitors with triazole-linked cap group.EBI
Georgia Institute of Technology
Pocket detection and interaction-weighted ligand-similarity search yields novel high-affinity binders for Myocilin-OLF, a protein implicated in glaucoma.EBI
Georgia Institute of Technology
Heteroaryl compounds as sodium channel blockersBDB
Purdue Pharma
Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitorsBDB
Allergan