35 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Design, synthesis and evaluation of antiproliferative activity of melanoma-targeted histone deacetylase inhibitors.
Georgia Institute of Technology
Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase.
Georgia Institute of Technology
Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions.
Georgia Institute of Technology
Design and structure activity relationship of tumor-homing histone deacetylase inhibitors conjugated to folic and pteroic acids.
Georgia Institute of Technology
The antileishmanial activity of isoforms 6- and 8-selective histone deacetylase inhibitors.
Georgia Institute of Technology
3-Hydroxypyridin-2-thione as novel zinc binding group for selective histone deacetylase inhibition.
Georgia Institute of Technology
Dual targeting of histone deacetylase and topoisomerase II with novel bifunctional inhibitors.
Georgia Institute of Technology
Design and synthesis of novel histone deacetylase inhibitor derived from nuclear localization signal peptide.
Georgia Institute of Technology
Aza-peptidyl Michael acceptor and epoxide inhibitors--potent and selective inhibitors of Schistosoma mansoni and Ixodes ricinus legumains (asparaginyl endopeptidases).
Georgia Institute of Technology
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: restricted rotation analogues of methylphenidate.
Georgia Institute of Technology
Synthesis and pharmacology of site specific cocaine abuse treatment agents: 8-substituted isotropane (3-azabicyclo[3.2.1]octane) dopamine uptake inhibitors.
Georgia Institute of Technology
Syntheses and biological activities of a novel group of steroidal derived inhibitors for human Cdc25A protein phosphatase.
Georgia Institute of Technology
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-(aminomethyl)-3-phenylbicyclo[2.2.2]- and -[2.2.1]alkane dopamine uptake inhibitors.
Georgia Institute of Technology
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-substituted-6-amino-5-phenylbicyclo[2.2.2]octanes.
Georgia Institute of Technology
Synthesis and pharmacology of potential cocaine antagonists. 2. Structure-activity relationship studies of aromatic ring-substituted methylphenidate analogs.
Georgia Institute of Technology
Novel anthraquinone inhibitors of human leukocyte elastase and cathepsin G.
Georgia Institute of Technology
Unexpected inhibition of S-adenosyl-L-homocysteine hydrolase by a guanosine nucleoside.
Georgia Institute of Technology
Peptidyl alpha-ketoamides with nucleobases, methylpiperazine, and dimethylaminoalkyl substituents as calpain inhibitors.
Georgia Institute of Technology
Non-peptide macrocyclic histone deacetylase inhibitors derived from tricyclic ketolide skeleton.
Georgia Institute of Technology
Synthetic methodology-enabled discovery of a tunable indole template for COX-1 inhibition and anti-cancer activity.
Georgia Institute of Technology
Pyrimethamine conjugated histone deacetylase inhibitors: Design, synthesis and evidence for triple negative breast cancer selective cytotoxicity.
Georgia Institute of Technology
Novel small molecule binders of human N-glycanase 1, a key player in the endoplasmic reticulum associated degradation pathway.
Georgia Institute of Technology
Novel peptidyl alpha-keto amide inhibitors of calpains and other cysteine proteases.
Georgia Institute of Technology
A structure-activity relationship of non-peptide macrocyclic histone deacetylase inhibitors and their anti-proliferative and anti-inflammatory activities.
Georgia Institute of Technology
Ligand binding studies, preliminary structure-activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inhibitors of Escherichia coli dihydrofolate reductase.
Georgia Institute of Technology
Synthesis and structure-activity relationship of 3-hydroxypyridine-2-thione-based histone deacetylase inhibitors.
Georgia Institute of Technology
Peptide alpha-keto ester, alpha-keto amide, and alpha-keto acid inhibitors of calpains and other cysteine proteases.
Georgia Institute of Technology
Histone deacetylase inhibitors equipped with estrogen receptor modulation activity.
Georgia Institute of Technology
Dual-acting histone deacetylase-topoisomerase I inhibitors.
Georgia Institute of Technology
Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group.
Georgia Institute of Technology
Synthesis and structure-activity relationship of histone deacetylase (HDAC) inhibitors with triazole-linked cap group.
Georgia Institute of Technology
Pocket detection and interaction-weighted ligand-similarity search yields novel high-affinity binders for Myocilin-OLF, a protein implicated in glaucoma.
Georgia Institute of Technology
