PMID

Data

Article Title

Organization

Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1).

University of California

Pharmacokinetics and hepatic uptake of eltrombopag, a novel platelet-increasing agent.

Kanazawa University

The cation transporters rOCT1 and rOCT2 interact with bicarbonate but play only a minor role for amantadine uptake into rat renal proximal tubules.

University of Manitoba

The synthesis and biodistribution of [(11)C]metformin as a PET probe to study hepatobiliary transport mediated by the multi-drug and toxin extrusion transporter 1 (MATE1) in vivo.

Riken Center For Life Science Technologies

Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.

University of California

Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.

Institute of Anatomy of The Bayerische Julius-Maximilians-Universit£T

Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney.

Tokyo University of Science

Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes.

Kyoto University Hospital

Functional characterization of mouse cation transporter mOCT2 compared with mOCT1.

Kyushu University

Interactions of n-tetraalkylammonium compounds and biguanides with a human renal organic cation transporter (hOCT2).

University of California

Kinetic and selectivity differences between rodent, rabbit, and human organic cation transporters (OCT1).

University of California

Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3.

University of Bonn

Transport of small organic cations in the rat liver. The role of the organic cation transporter OCT1.

University of Heidelberg

Drug excretion mediated by a new prototype of polyspecific transporter.

Bayerische Julius-Maximilians-Universit£T

Selective substrates for non-neuronal monoamine transporters.

University of Heidelberg

Agmatine is efficiently transported by non-neuronal monoamine transporters extraneuronal monoamine transporter (EMT) and organic cation transporter 2 (OCT2).

University of Cologne

Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1.

University of Arizona

Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.

Kyoto University Hospital

Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.

Kyoto University Hospital

Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

University of California San Francisco

Role of organic cation transporters in the renal secretion of nucleosides.

The University of Texas M.D. Anderson Cancer Center

Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

Uppsala University

Selective Inhibition of Organic Cation Transporter 1 by Benzoylpaeoniflorin Attenuates Hepatic Lipid Accumulation through AMPK Activation.

Tianjin University

Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1.

University Medicine Greifswald

Cloning and functional expression of a human liver organic cation transporter.

University of California San Francisco

The interaction of n-tetraalkylammonium compounds with a human organic cation transporter, hOCT1.

University of California San Francisco

Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).

University of California

Interactions of HIV protease inhibitors with a human organic cation transporter in a mammalian expression system.

University of California

Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate.

Bayerische Julius-Maximilians-Universit£T

A new chemotype inhibitor for the human organic cation transporter 3 (hOCT3).

Virginia Commonwealth University

Styryl quinazoline derivatives as pharmaceutically active agents

Vichem Chemie Kutató

Compounds as rearranged during transfection (RET) inhibitors

Glaxosmithkline

Benzimidazole derivatives as RLK and ITK inhibitors

Principia Biopharma

Pyridazinone compounds and their use as DAAO inhibitors

Takeda Pharmaceutical

Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis.

Kochi Medical School

Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes.

Universita Del Piemonte Orientale

Carbonic anhydrase inhibitors. Comparison of chlorthalidone, indapamide, trichloromethiazide, and furosemide X-ray crystal structures in adducts with isozyme II, when several water molecules make the difference.

Universita Degli Studi Di Firenze