Binding Database

BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.0M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 685K Compounds and 4.6K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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12 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors

Vtv Therapeutics

Phosphatidylinositol 3-kinase inhibitors

Gilead Sciences

Purine inhibitors of human phosphatidylinositol 3-kinase delta

Merck Sharp & Dohme

N-(phenylsulfonyl)benzamides and related compounds as BCL-2 inhibitors

The Regents of The University of Michigan

Pharmaceutical formulations comprising CCR3 antagonists

Alkahest

Design and synthesis of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 1.

Gnf

Identification of a potent and selective non-basic cathepsin K inhibitor.

Merck Frosst Centre For Therapeutic Research

The identification of potent, selective, and bioavailable cathepsin S inhibitors.

Merck Frosst Centre For Therapeutic Research

Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta.

Ghent University

Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains.

University of Illinois At Urbana-Champaign

Benzothiophene selective estrogen receptor modulators with modulated oxidative activity and receptor affinity.

University of Illinois At Chicago

Toward Potent Ghrelin Receptor Ligands Based on Trisubstituted 1,2,4-Triazole Structure. 2. Synthesis and Pharmacological in Vitro and in Vivo Evaluations.

Cnrs