The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.0M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 685K Compounds and 4.6K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Advanced Search

29 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Inhibition of the Aldehyde Dehydrogenase 1/2 Family by Psoralen and Coumarin Derivatives.EBI
Indiana University School of Medicine
Characterization of two distinct structural classes of selective aldehyde dehydrogenase 1A1 inhibitors.EBI
Indiana University
Development of selective inhibitors for aldehyde dehydrogenases based on substituted indole-2,3-diones.EBI
Indiana University School of Medicine
Structure-activity relationship studies and biological characterization of human NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.EBI
National Center For Advancing Translational Sciences
Aldehyde dehydrogenase inhibitors: alpha,beta-acetylenic N-substituted aminothiolesters are reversible growth inhibitors of normal epithelial but irreversible apoptogens for cancer epithelial cells from human prostate in culture.EBI
Claude Bernard University Lyon 1
Scaffold hopping based designing of selective ALDH1A1 inhibitors to overcome cyclophosphamide resistance: synthesis and biological evaluation.EBI
Punjabi University
Cytosolic Enzymes Generate Cannabinoid Metabolites 7-Carboxycannabidiol and 11-Nor-9-carboxytetrahydrocannabinol.EBI
University of North Carolina at Chapel Hill
Discovery and development of selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors.EBI
China Pharmaceutical University
Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer.EBI
University of Bradford
Conjugates Derived from Lapatinib Derivatives with Cancer Cell Stemness Inhibitors Effectively Reversed Drug Resistance in Triple-Negative Breast Cancer.EBI
Southeast University
Discovery of benzimidazole derivatives as potent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with glucose consumption improving activity.EBI
China Pharmaceutical University
Development of new disulfiram analogues as ALDH1a1-selective inhibitors.EBI
Umm Al-Qura University
Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy.EBI
University of Michigan
Discovery of 5-(3-Chlorophenylamino)benzo[EBI
Southeast University
Design, synthesis characterization and biological evaluation of novel multi-isoform ALDH inhibitors as potential anticancer agents.EBI
The Pennsylvania State University College of Medicine
Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2-EBI
University of Pisa
Discovery of coumarin-based selective aldehyde dehydrogenase 1A1 inhibitors with glucose metabolism improving activity.EBI
China Pharmaceutical University
Imidazo[1,2-EBI
University of Pisa
Diethylcarbamoylating/nitroxylating agents as dual action inhibitors of aldehyde dehydrogenase: a disulfiram-cyanamide merger.EBI
Va Medical Center
Prodrugs of nitroxyl and nitrosobenzene as cascade latentiated inhibitors of aldehyde dehydrogenase.EBI
St. Cloud State University
Carbethoxylating agents as inhibitors of aldehyde dehydrogenase.EBI
University of Minnesota
Prodrugs of nitroxyl as potential aldehyde dehydrogenase inhibitors vis-a-vis vascular smooth muscle relaxants.EBI
University of Minnesota
Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes.EBI
University of Oklahoma Health Sciences Center
Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy.EBI
Indiana University School of Medicine
Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.EBI
National Center For Advancing Translational Sciences
Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase.EBI
University of Minnesota
ROR-GAMMA MODULATORSBDB
Escalier Biosciences
Aminomethyl-4-imidazolesBDB
Hoffmann-La Roche
Systems-based design of bi-ligand inhibitors of oxidoreductases: filling the chemical proteomic toolbox.BDB
Triad Therapeutics