PMID

Data

Article Title

Organization

Receptor-ligand interaction-based virtual screening for novel Eg5/kinesin spindle protein inhibitors.

Korea Institute of Science and Technology

Substituted benzimidazoles: A novel chemotype for small molecule hKSP inhibitors.

Schering-Plough Research Institute

Kinesin spindle protein (KSP) inhibitors. 9. Discovery of (2S)-4-(2,5-difluorophenyl)-n-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the treatment of taxane-refractory cancer.

Merck Research Laboratories