PMID

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Article Title

Organization

Investigations into specificity of azepinomycin for inhibition of guanase: discrimination between the natural heterocyclic inhibitor and its synthetic nucleoside analogues.

University of Maryland

A novel transition state analog inhibitor of guanase based on azepinomycin ring structure: Synthesis and biochemical assessment of enzyme inhibition.

TBA

A unique ring-expanded acyclic nucleoside analogue that inhibits both adenosine deaminase (ADA) and guanine deaminase (GDA; guanase): synthesis and enzyme inhibition studies of 4,6-diamino-8H-1-hydroxyethoxymethyl-8-iminoimidazo[4,5-e][1,3]diazepine.

University of Maryland

Identification of small molecule compounds with higher binding affinity to guanine deaminase (cypin) than guanine.

The State University of New Jersey

Design of inhibitors against guanase: synthesis and biochemical evaluation of analogues of azepinomycin.

University of Maryland

Synthesis and guanase inhibition studies of a novel ring-expanded purine analogue containing a 5:7-fused, planar, aromatic heterocyclic ring system.

University of Maryland