9 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Synthesis and biological evaluation of a unique heparin mimetic hexasaccharide for structure-activity relationship studies.
Momenta Pharmaceuticals
Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies.
TBA
Hedgehog-Gli signaling pathway inhibitors as anticancer agents.
St. Jude Children'S Research Hospital
Identification, characterization, and implications of species-dependent plasma protein binding for the oral Hedgehog pathway inhibitor vismodegib (GDC-0449).
Genentech
A small molecule that binds Hedgehog and blocks its signaling in human cells.
Broad Institute of Harvard and Massachusetts Institute of Technology
Syntheses of aminoalcohol-derived macrocycles leading to a small-molecule binder to and inhibitor of Sonic Hedgehog.
Massachusetts General Hospital
Current approaches and strategies to identify Hedgehog signaling pathway inhibitors for cancer therapy.
Peking Union Medical College
Cyclic Peptide Screening Methods for Preclinical Drug Discovery.
University of Washington