The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.0M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 695K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Advanced Search

9 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis and biological evaluation of a unique heparin mimetic hexasaccharide for structure-activity relationship studies.EBI
Momenta Pharmaceuticals
Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies.EBI
TBA
Hedgehog-Gli signaling pathway inhibitors as anticancer agents.EBI
St. Jude Children'S Research Hospital
Identification, characterization, and implications of species-dependent plasma protein binding for the oral Hedgehog pathway inhibitor vismodegib (GDC-0449).EBI
Genentech
A small molecule that binds Hedgehog and blocks its signaling in human cells.EBI
Broad Institute of Harvard and Massachusetts Institute of Technology
Syntheses of aminoalcohol-derived macrocycles leading to a small-molecule binder to and inhibitor of Sonic Hedgehog.EBI
Massachusetts General Hospital
Current approaches and strategies to identify Hedgehog signaling pathway inhibitors for cancer therapy.EBI
Peking Union Medical College
Cyclic Peptide Screening Methods for Preclinical Drug Discovery.EBI
University of Washington
Inhibiting Hedgehog: An Update on Pharmacological Compounds and Targeting Strategies.EBI
Philipps University Marburg