PMID

Data

Article Title

Organization

Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: optimising brain penetration.

F. Hoffmann-La Roche

Buspirone analogues. 2. Structure-activity relationships of aromatic imide derivatives.

TBA

 

Derivatives of 2-arylcyclopropylamine: Synthesis and interactions with 5-HT_1A receptors.

TBA

N-Arylsulfonylindole derivatives as serotonin 5-HT(6) receptor ligands.

Merck Sharp & Dohme Research Laboratories

Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives.

Solvay Duphar

Synthesis and evaluation of a novel series of N,N-dimethylisotryptamines.

TBA

ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties: I. In vitro characterization and acute antinociceptive effects in the mouse.

Abbott Laboratories

Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.

Sri International

Molecular biology of 5-HT receptors.

University of Alberta

Two members of a distinct subfamily of 5-hydroxytryptamine receptors differentially expressed in rat brain.

The Scripps Research Institute