PMID

Data

Article Title

Organization

Bacterial versus human sphingosine-1-phosphate lyase (S1PL) in the design of potential S1PL inhibitors.

Institute For Advanced Chemistry of Catalonia (Iqac-Csic)

Orally active 7-substituted (4-benzylphthalazin-1-yl)-2-methylpiperazin-1-yl]nicotinonitriles as active-site inhibitors of sphingosine 1-phosphate lyase for the treatment of multiple sclerosis.

Novartis Institutes For Biomedical Research

Studies on the inhibition of sphingosine-1-phosphate lyase by stabilized reaction intermediates and stereodefined azido phosphates.

Spanish National Research Council (Csic)

Hit-to-lead evaluation of a novel class of sphingosine 1-phosphate lyase inhibitors.

Abbvie

Substituted bicyclic compounds

Bristol-Myers Squibb