PMID

Data

Article Title

Organization

Variation of the aryl substituent on the piperazine ring within the 4-(piperazin-1-yl)-2,6-di(pyrrolidin-1-yl)pyrimidine scaffold unveils potent, non-competitive inhibitors of the inflammatory caspases.

Depaul University

Irreversible inhibitors of cysteine proteases.

Dart Neuroscience

Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation.

University of Florida

Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB.

National Human Genome Research Institute

Novel pyrazinone mono-amides as potent and reversible caspase-3 inhibitors.

Merck Frosst Centre For Therapeutic Research

Synthesis and antitumor activities of 1,2,3-triazines and their benzo- and heterofused derivatives.

University of Palermo

Non-steroidal Anti-inflammatory Drugs Are Caspase Inhibitors.

University of Colorado

Selective caspase inhibitors and uses thereof

Novagenesis Foundation

Potent and selective nonpeptide inhibitors of caspases 3 and 7.

Glaxosmithkline

Identification of potent and selective small-molecule inhibitors of caspase-3 through the use of extended tethering and structure-based drug design.

Sunesis Pharmaceuticals