PMID

Data

Article Title

Organization

Synthesis and SAR of calcitonin gene-related peptide (CGRP) antagonists containing substituted aryl-piperazines and piperidines.

Bristol-Myers Squibb Discovery

Identification of a novel RAMP-independent CGRP receptor antagonist.

Merck Research Laboratories

Identification of potent, selective, and metabolically stable peptide antagonists to the calcitonin gene-related peptide (CGRP) receptor.

Amgen

Pyrazolotriazines: Biological activities, synthetic strategies and recent developments.

Mazandaran University of Medical Sciences

CGRP receptor antagonists

Heptares Therapeutics

CGRP receptor antagonists

Merck Sharp & Dohme

SR147778 [5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a new potent and selective antagonist of the CB1 cannabinoid receptor: biochemical and pharmacological characterization.

Sanofi-Synthelabo Recherche