PMID

Data

Article Title

Organization

Small Molecule Lysyl Oxidase-like 2 (LOXL2) Inhibitors: The Identification of an Inhibitor Selective for LOXL2 over LOX.

Pharmakea

Alkylamino derivatives of 4-aminomethylpyridine as inhibitors of copper-containing amine oxidases.

University of Genoa

4-(5-Amino-pyrazol-1-yl)benzenesulfonamide derivatives as novel multi-target anti-inflammatory agents endowed with inhibitory activity against COX-2, 5-LOX and carbonic anhydrase: Design, synthesis, and biological assessments.

Damanhour University

Indanylidenes. 1. Design and synthesis of (E)-2-(4,6-difluoro-1-indanylidene)acetamide, a potent, centrally acting muscle relaxant with antiinflammatory and analgesic activity.

Glaxosmithkline

Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3.

Pharmaxis

Inhibition of the LOX enzyme family members with old and new ligands. Selectivity analysis revisited.

Hungarian Academy of Sciences

Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2).

Pharmakea Therapeutics

Uses of a lysyl oxidase-like 2 inhibitor

Pharmakea

Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer

The Institute of Cancer Research: Royal Cancer Hospital

Alpha-1-C-octyl-1-deoxynojirimycin as a pharmacological chaperone for Gaucher disease.

Hokuriku University