BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.0M data for 1.3M Compounds and 9.5K Targets. Of those, 1.4M data for 679K Compounds and 4.6K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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9 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
N-Hydroxyimides and hydroxypyrimidinones as inhibitors of the DNA repair complex ERCC1-XPF.EBI
Mrc Technology
Catechols and 3-hydroxypyridones as inhibitors of the DNA repair complex ERCC1-XPF.EBI
Mrc Technology
The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors.EBI
Athersys
The identification and optimization of 2,4-diketobutyric acids as flap endonuclease 1 inhibitors.EBI
Athersys
Dihydrothieno[3,2-b]pyridine compoundsBDB
Ideaya Biosciences
3-hydroxy-quinazoline-2,4-dione derivatives and their use as nuclease modulatorsBDB
Ludwig Institute For Cancer Research
Flap modulatorsBDB
Janssen Pharmaceutica
FLAP modulatorsBDB
Janssen Pharmaceutica
Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site.BDB
University of Sheffield