46 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
2-Alkoxy-3-(sulfonylarylaminomethylene)-chroman-4-ones as potent and selective inhibitors of ectonucleotidases.
Forman Christian College (A Chartered University)
Identification of sulfonic acids as efficient ecto-5'-nucleotidase inhibitors.
Comsats Institute of Information Technology
Virtual screening identifies novel sulfonamide inhibitors of ecto-5'-nucleotidase.
Rheinische Friedrich-Wilhelms-Universit£T
Development of potent and selective inhibitors of ecto-5'-nucleotidase based on an anthraquinone scaffold.
University of Bonn
Combinatorial synthesis of anilinoanthraquinone derivatives and evaluation as non-nucleotide-derived P2Y2 receptor antagonists.
University of Bonn
Targeting ecto-5'-nucleotidase: A comprehensive review into small molecule inhibitors and expression modulators.
Federal University of Rio Grande Do Sul
Discovery of a Series of Potent, Selective, and Orally Bioavailable Nucleoside Inhibitors of CD73 That Demonstrates
Calithera Biosciences
Recent advances in small molecule based cancer immunotherapy.
Southern Medical University
Application of marine natural products in drug research.
Weihai Marine Organism & Medical Technology Research Institute
Discovery and optimization of betulinic acid derivatives as novel potent CD73 inhibitors.
The Second Military Medical University
Structure-Activity Relationship of 3-Methylcytidine-5'-α,β-methylenediphosphates as CD73 Inhibitors.
National Institute of Diabetes and Digestive and Kidney Diseases
Structure-activity relationships of pyrimidine nucleotides containing a 5'-α,β-methylene diphosphonate at the P2Y
National Institute of Diabetes and Digestive and Kidney Diseases
Discovery of Potent and Selective Methylenephosphonic Acid CD73 Inhibitors.
Arcus Biosciences
Orally Bioavailable Small-Molecule CD73 Inhibitor (OP-5244) Reverses Immunosuppression through Blockade of Adenosine Production.
Oric Pharmaceuticals
Discovery of natural product ellagic acid as a potent CD73 and CD39 dual inhibitor.
Ningxia Medical University
Targeting Metabolism of Extracellular Nucleotides via Inhibition of Ectonucleotidases CD73 and CD39.
Arcus Biosciences
Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73.
Arcus Biosciences
2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.
University of Bonn
Structure-Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5'-Nucleotidase (CD73) Inhibitors.
National Institute of Diabetes and Digestive and Kidney Diseases
Lead optimization and biological evaluation of fragment-based cN-II inhibitors.
University of Montpellier
CD73 inhibition by purine cytotoxic nucleoside analogue-based diphosphonates.
Claude Bernard University Lyon 1
Inhibitors of CD73 May Provide a Treatment for Cancer and Autoimmune Diseases.
Therachem Research Medilab (India)
MODULATORS OF A POTASSIUM CHANNEL AND OF TRPV1 CHANNEL AND USES THEREOF
Bsense Bio Therapeutics
AROMATIC HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF
Gt Apeiron Therapeutics
PYRAZOLO DERIVATIVES AS HUMAN DIHYDROOROTATE DEHYDROGENASE (HDHODH) INHIBITORS FOR USE AS ANTIVIRALS
Drug Discovery and Clinic
INHIBITORS OF THE INTERACTION BETWEEN TRIP8B AND HCN CHANNELS AND USES THEREOF FOR TREATING NEUROLOGICAL DISEASES AND DISORDERS
Northwestern University
SALT OF DIHYDROPYRIDO[2,3-D]PYRIMIDINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF
Nanjing Chia Tai Tianqing Pharmaceutical
Cyano-substituted heterocycles with activity as inhibitors of USP30
Mission Therapeutics
Pyridine quinoline compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
Vanderbilt University
Substituted isoindolin-1-ones and 2,3-dihydro-1h-pyrrolo[3,4-c]pyridin-1-ones as hpk1 antagonists
Nimbus Saturn
Heteroaryl substituted benzoic acids as RORgammaT inhibitors and uses thereof
Merck Sharp & Dohme
Aminoindane-, aminotetrahydronaphthalene- and aminobenzocyclobutane-derived PRMT5-inhibitors
Ctxt
Meta-substituted phenyl sulfonyl amides of secondary amino acid amides, the production thereof, and use thereof as matriptase inhibitors
The Medicines Company (Leipzig)
Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors.
Duquesne University
4-(1,1-Dioxo-1,4-dihydro-1lambda6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase.
Anadys Pharmaceuticals
Pharmacological and functional comparison of the polo-like kinase family: insight into inhibitor and substrate specificity.
Abbott Laboratories
Substituted pyrrolo[2,3-b]pyridines as inhibitors of cellular necroptosis
Institut National De La Sante Et De La Recherche Medicale (Inserm)