21 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Structure-Activity Relationship Studies and Molecular Modeling of Naphthalene-Based Sphingosine Kinase 2 Inhibitors.
Virginia Tech
Structure-activity relationship studies of the lipophilic tail region of sphingosine kinase 2 inhibitors.
Virginia Tech
Difluoromethyl ketones: Potent inhibitors of wild type and carbamate-insensitive G119S mutant Anopheles gambiae acetylcholinesterase.
Virginia Tech
Structure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors.
Virginia Tech
3-Oxoisoxazole-2(3H)-carboxamides and isoxazol-3-yl carbamates: Resistance-breaking acetylcholinesterase inhibitors targeting the malaria mosquito, Anopheles gambiae.
Virginia Tech
Design, synthesis and biological activity of sphingosine kinase 2 selective inhibitors.
Virginia Tech
Triazole-linked reduced amide isosteres: an approach for the fragment-based drug discovery of anti-Alzheimer's BACE1 inhibitors.
Virginia Tech
2-Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2).
Virginia Tech
Semisynthetic blasticidin S ester derivatives show enhanced antibiotic activity.
Virginia Tech
Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors.
Virginia Tech
Probing the substitution pattern of indole-based scaffold reveals potent and selective sphingosine kinase 2 inhibitors.
Virginia Tech
Lipophilic tail modifications of 2-(hydroxymethyl)pyrrolidine scaffold reveal dual sphingosine kinase 1 and 2 inhibitors.
Virginia Tech
Discovery and antiparasitic activity of AZ960 as a Trypanosoma brucei ERK8 inhibitor.
Virginia Tech
Discovery of a Small Side Cavity in Sphingosine Kinase 2 that Enhances Inhibitor Potency and Selectivity.
Virginia Tech
Virtual Screening of CB2 Receptor Agonists from Bayesian Network and High-Throughput Docking: Structural Insights into Agonist-Modulated GPCR Features.
Universite Lille-Nord de France