46 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators.
University of Salerno
2,3-Dihydrobenzofuran privileged structures as new bioinspired lead compounds for the design of mPGES-1 inhibitors.
University of Salerno
A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach.
University of Salerno
Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors.
University of Salerno
Structural evidence of N6-isopentenyladenosine as a new ligand of farnesyl pyrophosphate synthase.
University of Salerno
Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1).
University of Salerno
Structure-activity relationship refinement and further assessment of 4-phenylquinazoline-2-carboxamide translocator protein ligands as antiproliferative agents in human glioblastoma tumors.
University of Salerno
Direct interaction of garcinol and related polyisoprenylated benzophenones of Garcinia cambogia fruits with the transcription factor STAT-1 as a likely mechanism of their inhibitory effect on cytokine signaling pathways.
University of Salerno
Discovery and biological evaluation of novel 1,4-benzoquinone and related resorcinol derivatives that inhibit 5-lipoxygenase.
University of Salerno
A chemical-biological study reveals C9-type iridoids as novel heat shock protein 90 (Hsp90) inhibitors.
University of Salerno
Bioassay-guided isolation of proanthocyanidins with antiangiogenic activities.
University of Salerno
Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1.
University of Salerno
Identification of new¿-hydroxybutenolides that preferentially inhibit the activity of mPGES-1.
University of Salerno
Synthesis and biological evaluation of 4-phenylquinazoline-2-carboxamides designed as a novel class of potent ligands of the translocator protein.
University of Salerno
Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors.
University of Salerno
Inverse Virtual Screening allows the discovery of the biological activity of natural compounds.
University of Salerno
Design, synthesis and biological evaluation of novel bicyclo[1.1.1]pentane-based omega-acidic amino acids as glutamate receptors ligands.
University of Salerno
Makaluvamine P, a new cytotoxic pyrroloiminoquinone from Zyzzya cf. fuliginosa.
University of Salerno
Synthesis and comparison of the antiinflammatory activity of manoalide and cacospongionolide B analogues.
University of Salerno
Synthesis and biochemical evaluation ofd(2)-isoxazoline derivatives as DNA methyltransferase 1 inhibitors.
University of Salerno
Structure-based discovery of inhibitors of microsomal prostaglandin E2 synthase-1, 5-lipoxygenase and 5-lipoxygenase-activating protein: promising hits for the development of new anti-inflammatory agents.
University of Salerno
Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222.
University of Salerno
Synthesis and biological evaluation of new potential inhibitors of N-acylethanolamine hydrolyzing acid amidase.
University of Salerno
2-Substituted 1,5-benzothiazepine-based HDAC inhibitors exert anticancer activities on human solid and acute myeloid leukemia cell lines.
University of Salerno
Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor.
University of Salerno
Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis.
University of Salerno
Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders.
University of Salerno
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E
University of Salerno
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity.
University of Salerno
New Aβ(1-42) ligands from anti-amyloid antibodies: Design, synthesis, and structural interaction.
University of Salerno
New TRPM8 blockers exert anticancer activity over castration-resistant prostate cancer models.
University of Salerno
Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization.
University of Salerno
Structure-based screening for the discovery of 1,2,4-oxadiazoles as promising hits for the development of new anti-inflammatory agents interfering with eicosanoid biosynthesis pathways.
University of Salerno
Exploration of TRPM8 Binding Sites by β-Carboline-Based Antagonists and Their In Vitro Characterization and In Vivo Analgesic Activities.
University of Salerno
Targeting mPGES-1 by a Combinatorial Approach: Identification of the Aminobenzothiazole Scaffold to Suppress PGE
University of Salerno
Fusicoccane Diterpenes from Hypoestes forsskaolii as Heat Shock Protein 90 (Hsp90) Modulators.
University of Salerno
Dimeric and trimeric triazole based molecules as a new class of Hsp90 molecular chaperone inhibitors.
University of Salerno
Progresses in the pursuit of aldose reductase inhibitors: the structure-based lead optimization step.
University of Salerno
Identification of a Potent Tryptophan-Based TRPM8 Antagonist With in Vivo Analgesic Activity.
University of Salerno
Discovery of new potent molecular entities able to inhibit mPGES-1.
University of Salerno
Identification by Inverse Virtual Screening of magnolol-based scaffold as new tankyrase-2 inhibitors.
University of Salerno
Discovery of new erbB4 inhibitors: Repositioning an orphan chemical library by inverse virtual screening.
University of Salerno