26 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
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Article Title
Organization
Docking of competitive inhibitors to the P2X7 receptor family reveals key differences responsible for changes in response between rat and human.
University of Leeds
(±) cis-Bisamido epoxides: A novel series of potent FXIII-A inhibitors.
University of Leeds
Pyridine-3-carboxamide-6-yl-ureas as novel inhibitors of bacterial DNA gyrase: structure based design, synthesis, SAR and antimicrobial activity.
University of Leeds
The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target.
University of Leeds
Development of a triclosan scaffold which allows for adaptations on both the A- and B-ring for transport peptides.
University of Leeds
Discovery of biphenylacetamide-derived inhibitors of BACE1 using de novo structure-based molecular design.
University of Leeds
Factors influencing the specificity of inhibitor binding to the human and malaria parasite dihydroorotate dehydrogenases.
University of Leeds
Discovery of novel non-peptide inhibitors of BACE-1 using virtual high-throughput screening.
University of Leeds
Design, synthesis and in vitro evaluation of novel bivalent S-adenosylmethionine analogues.
University of Leeds
Recent developments in the structural characterisation of the IR and IGF1R: implications for the design of IR-IGF1R hybrid receptor modulators.
University of Leeds
design of type II topoisomerase inhibitors as potential antimicrobial agents targeting a novel binding region.
University of Leeds
From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor.
University of Leeds
Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis.
University of Leeds
Spatial requirements of the antagonist binding site of the NK2 receptor.
University of Leeds
New insights into the binding mode of pyridine-3-carboxamide inhibitors of E. coli DNA gyrase.
University of Leeds
Identification of an Indazole-Based Pharmacophore for the Inhibition of FGFR Kinases Using Fragment-Led
University of Leeds
Interconvertible geometric isomers of Plasmodium falciparum dihydroorotate dehydrogenase inhibitors exhibit multiple binding modes.
University of Leeds
In Silico Fragment-Based Design Identifies Subfamily B1 Metallo-β-lactamase Inhibitors.
University of Leeds
Geminal substituted quinuclidine amide compounds as agonists of α-7 nicotonic acetylcholine receptors
Axovant Sciences
Tricyclic compounds for use as kinase inhibitors
FundaciÓN Centro Nacional De Investigaciones Oncologicas Carlos Iii
Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety
Endorecherche
3,4-dihydro-2H-isoquinoline-1-one and 2,3-dihydro-isoindol-1-one compounds
Hoffmann-La Roche