PMID

Data

Article Title

Organization

Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase.

University of Edinburgh

AXL Inhibitors in Cancer: A Medicinal Chemistry Perspective.

University of Edinburgh

Modulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by 1,5-substituted 1H-tetrazoles.

University of Edinburgh

Design, synthesis and trypanocidal activity of lead compounds based on inhibitors of parasite glycolysis.

University of Edinburgh

Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors.

University of Edinburgh

Discovery of pyrazolopyrimidines that selectively inhibit CSF-1R kinase by iterative design, synthesis and screening against glioblastoma cells.

University of Edinburgh

Synthesis of novel caspase inhibitors for characterization of the active caspase proteome in vitro and in vivo.

University of Edinburgh

Small Molecule Kinase Inhibitor Drugs (1995-2021): Medical Indication, Pharmacology, and Synthesis.

University of Edinburgh

Recent developments in anticancer kinase inhibitors based on the pyrazolo[3,4-

University of Edinburgh

Pyrazolopyrimide library screening in glioma cells discovers highly potent antiproliferative leads that target the PI3K/mTOR pathway.

University of Edinburgh

Blinded predictions of binding modes and energies of HSP90-α ligands for the 2015 D3R grand challenge.

University of Edinburgh

Development of Potent Inhibitors of Receptor Tyrosine Kinases by Ligand-Based Drug Design and Target-Biased Phenotypic Screening.

University of Edinburgh

Identification of a small molecule beta-secretase inhibitor that binds without catalytic aspartate engagement.

Merck Research Laboratories

Novel 4-aminoquinolines active against chloroquine-resistant and sensitive P. falciparum strains that also inhibit botulinum serotype A.

University of Belgrade