PMID

Data

Article Title

Organization

Selective inhibition of mammalian lanosterol 14 alpha-demethylase: a possible strategy for cholesterol lowering.

Syntex Discovery Research

4,6-disubstituted aminopyrimidine derivatives have anti-HIV activity

Virostatics

Botulinum neurotoxin serotype A inhibitors: small-molecule mercaptoacetamide analogs.

Absolute Science

Investigation on the role of the tetrazole in the binding of thiotetrazolylacetanilides with HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases.

Boehringer Ingelheim (Canada)

Identification and structure-activity relationships of substituted pyridones as inhibitors of Pim-1 kinase.

Valeant Pharmaceuticals Research and Development

Docking study yields four novel inhibitors of the protooncogene Pim-1 kinase.

Vertex Pharmaceuticals

Potent, selective, orally bioavailable inhibitors of tumor necrosis factor-alpha converting enzyme (TACE): discovery of indole, benzofuran, imidazopyridine and pyrazolopyridine P1' substituents.

Bristol-Myers Squibb