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Solution-phase microwave assisted parallel synthesis, biological evaluation and in silico docking studies of N,N'-disubstituted thioureas derived from 3-chlorobenzoic acid.

Quaid-I-Azam University

Quinazolines and quinazolinones as ubiquitous structural fragments in medicinal chemistry: An update on the development of synthetic methods and pharmacological diversification.

Quaid-I-Azam University

Isocoumarins, miraculous natural products blessed with diverse pharmacological activities.

Quaid-I-Azam University

Synthesis, characterization, hypoglycemic and aldose reductase inhibition activity of arylsulfonylspiro[fluorene-9,5'-imidazolidine]-2',4'-diones.

Quaid-I-Azam University

Recent advances in the structural library of functionalized quinazoline and quinazolinone scaffolds: synthetic approaches and multifarious applications.

Quaid-I-Azam University

Active compounds from a diverse library of triazolothiadiazole and triazolothiadiazine scaffolds: synthesis, crystal structure determination, cytotoxicity, cholinesterase inhibitory activity, and binding mode analysis.

Quaid-I-Azam University

Synthesis, crystal structure and biological evaluation of some novel 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines.

Quaid-I-Azam University

Synthesis, cytotoxicity and molecular modelling studies of new phenylcinnamide derivatives as potent inhibitors of cholinesterases.

Quaid-I-Azam University

Solution-phase microwave assisted parallel synthesis of N,N'-disubstituted thioureas derived from benzoic acid: biological evaluation and molecular docking studies.

Quaid-I-Azam University

Triazolothiadiazoles and triazolothiadiazines--biologically attractive scaffolds.

Quaid-I-Azam University

Synthesis, antioxidant activities and urease inhibition of some new 1,2,4-triazole and 1,3,4-thiadiazole derivatives.

Quaid-I-Azam University

Solid-phase synthesis and biological evaluation of a parallel library of 2,3-dihydro-1,5-benzothiazepines.

Quaid-I-Azam University

Synthetic α-glucosidase inhibitors as promising anti-diabetic agents: Recent developments and future challenges.

Quaid-I-Azam University

Enzyme inhibitory activities an insight into the structure-Activity relationship of biscoumarin derivatives.

Quaid-I-Azam University

Synthesis of biphenyl oxazole derivatives via Suzuki coupling and biological evaluations as nucleotide pyrophosphatase/phosphodiesterase-1 and -3 inhibitors.

Quaid-I-Azam University

Developing new hybrid scaffold for urease inhibition based on carbazole-chalcone conjugates: Synthesis, assessment of therapeutic potential and computational docking analysis.

Quaid-I-Azam University

Synthesis of new arylsulfonylspiroimidazolidine-2',4'-diones and study of their effect on stimulation of insulin release from MIN6 cell line, inhibition of human aldose reductase, sorbitol accumulations in various tissues and oxidative stress.

Quaid-I-Azam University

Exploration of carboxy pyrazole derivatives: Synthesis, alkaline phosphatase, nucleotide pyrophosphatase/phosphodiesterase and nucleoside triphosphate diphosphohydrolase inhibition studies with potential anticancer profile.

Quaid-I-Azam University

Design, synthesis, kinetic mechanism and molecular docking studies of novel 1-pentanoyl-3-arylthioureas as inhibitors of mushroom tyrosinase and free radical scavengers.

Quaid-I-Azam University

Synthesis of sulfadiazinyl acyl/aryl thiourea derivatives as calf intestinal alkaline phosphatase inhibitors, pharmacokinetic properties, lead optimization, Lineweaver-Burk plot evaluation and binding analysis.

Quaid-I-Azam University

Compounds and compositions as inhibitors of MEK

Novartis

Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use

F. Hoffmann-La Roche

Meta-substituted phenyl sulfonyl amides of secondary amino acid amides, the production thereof, and use thereof as matriptase inhibitors

The Medicines Company (Leipzig)

6,7-unsaturated-7-carbamoyl substituted morphinan derivative

Shionogi

Synthesis and in vitro opioid activity profiles of DALDA analogues.

Clinical Research Institute of Montreal

Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.

University of Virginia